The process of discharge or release of emotional tension associated with a repressed conflict, memory, or idea and often accompanied by the recall of a painful experience. As a technique it was introduced originally by Breuer (1842-1925) in a psychoanalytical context, but the term has since been broadened and has entered general parlance.
1. Excessive or improper use of substances, e.g. alcohol or other drugs, which may result in damage to health or increased risk of such damage.
2. Mistreatment; harming or injuring another.
Slowness or inadequacy in adapting to the demands of a new environment with which the individual could reasonably be expected to cope.
See dependence syndrome.
A disorder characterized by two or more episodes in which the patient's mood and activity levels are significantly disturbed. This disturbance consists on some occasions of an elevation of mood and increased energy and activity, and on others of a lowering of mood and decreased energy and activity.
Physiological mechanism that controls periodic changes or rhythms in various physical and behavioural functions, e.g. body temperature or blood pressure.See also: circadian oscillator.
See personality disorder, emotionally unstable.
Tumour originating within the brain, or intracerebral metastasis of neoplasms with a primary site elsewhere in the body. Both commonly produce a variety of mental symptoms (impairment of consciousness, cognitive deterioration, hallucinations and other psychotic phenomena, and affective changes), in addition to the signs of raised intracranial pressure, focal neurological signs, and epileptic seizures. In some cases, psychiatric symptoms may long precede the development of overt neurological signs.
See personality disorder, emotionally unstable.
Repeated bouts of overeating and an excessive preoccupation with the control of body weight, leading to a pattern of overeating followed by vomiting or use of purgatives. Repeated vomiting often causes electrolyte disturbances and physical complications. Bulimia nervosa is sometimes preceded, by a few months to several years, by an episode of anorexia nervosa. Synonym: hyperorexia nervosa
A state of physical or emotional exhaustion in response to the stress of unrelenting performance demands stemming from the individual’s occupation. Characteristics are: impaired work performance, fatigue, insomnia, depression, reliance on alcohol or other drugs of abuse for temporary relief, and sometimes suicide. The term is controversial and some authorities maintain that most cases of burn-out are clinical depressions.
Acute or chronic overuse of caffeine, i.e. a daily intake of 250 mg or more, leading to toxic manifestations such as restlessness, insomnia, facial flushing, muscle twitching, tachycardia, gastrointestinal disturbances including abdominal pain, pressured or rambling thought and speech, . and sometimes exacerbation of pre-existing anxiety or panic states, depression, or schizophrenia.
A response to exceptionally severe physical or mental stress, characterized by a breakdown of coping behaviour, intense anxiety, and shock. The term catastrophic reaction has also been applied to the state of agitation and helplessness exhibited by patients with cerebral damage when confronted with tasks beyond their competence (Goldstein, 1878-I965). See also: acute stress reaction
Maltreatment of a child, whether by neglect or by intentional exploitation or injuring. Child abuse may take many forms; in practice, combinations of different forms are the rule rather than the exception. Child neglect is the failure of the parent or care-giver to provide the child with adequate care and supervision. Physical abuse, sometimes referred to as the battered child syndrome, may involve physical violence, systematic poisoning, or other non-accidental injuries. Sexual abuse usually involves genital contact and may range in severity from fondling to forcible rape with physical injury. Child pornography and enforced prostitution are included. Psychological abuse refers to deliberate and repetitive subjection of a child to fear, rejection, humiliation, loneliness, and other painful psychological states.
pain Persisting or frequently recurring pain, not explicable by the degree of tissue pathology and unresponsive to the usual attempts to relieve it. The most common form of chronic intractable pain is back pain, especially of the lower back. See also: enduring personality change
A general term covering the acquisition of knowledge by means of any of various mental processes, such as conceptualization, perception, judgment, or imagination. Cognition is traditionally contrasted with conation (mental drive) and emotion.
A lasting and irreversible deterioration of any particular psychological function (e.g. cognitive defect), of the general development of mental capacities (mental defect), or of the characteristic pattern of thought, feeling, and behaviour that constitutes the individual personality. A defect in any one of these areas can be either innate or acquired. A characteristic defect state of the personality, ranging in its manifestations from loss of intellectual and emotional vigour and mild eccentricities of behaviour to autistic withdrawal or affective blunting, has been held by Kraepelin (1856-1926) and Eugen Bleuler (1857-1939) to be a hallmark of the outcome of schizophrenic illnesses, in contrast to manic-depressive psychosis.
A false, incorrigible conviction or judgement, out of keeping with reality and with the socially shared beliefs of the individual’s background and culture. Primary delusions are essentially incomprehensible in terms of the individual’s life history and personality; secondary delusions are psychologically com prehensible and arise from morbid and other states of mind, e.g. affective disorder or suspicion. A distinction was made, by Birnbaum in 1908 and Jaspers in 1913, between delusion proper and delusion-like ideas; the latter are merely mistaken judgements held with exaggerated tenacity.
A syndrome due to a disease of the brain, usually of a chronic or progressive nature, in which there is disturbance of multiple higher cortical functions, including memory, thinking, orientation, comprehension, calcu- lation, learning capacity, language, and judgement. Consciousness is not clouded. The cognitive impairments are commonly accompanied, and occasionally preceded, by deterioration in emotional control, social behaviour, or motivation.
A cluster of behavioural, cognitive, and physio logical phenomena that develop after repeated substance use. Typically they include a strong desire to take the substance, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to substance use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal state.The dependence syndrome may develop in relation to a specific substance (e.g. tobacco, alcohol, or diazepam), a class of substances (e.g. opioids), or a wider range of pharmacologically different psychoactive substances.
In lay terminology, a state of gloom, despondency, or sadness that may denote ill-health. In a medical context the term refers to a mental state dominated by a lowering of mood and often accompanied by a variety of associated symptoms, particularly anxiety, agitation, feelings of unworthiness, suicidal ideas, hypobulia, psychomotor retardation, and various somatic symptoms, physiological dysfunctions (e.g. insomnia), and complaints. As a symptom or a syndrome, depression is a major or significant feature in a variety of disease categories. The term is widely and sometimes imprecisely used to designate a symptom, a syndrome, and a disease state.
Any member of a group of disorders that includes anorexia nervosa, bulimia nervosa, overeating (psychogenic or associated with other psychological disturbances), vomiting (psychogenic or associated with other psychological disturbances), pica in adults, and loss of appetite (psychogenic).
An affective state of joyous gaiety which, when intensified and out of keeping with life circumstances, is a dominant symptom of mania and hypomania.
Abnormal concentration of one or more of the ions in the blood, such as sodium, potassium, calcium, and bicarbonate, usually secondary to some underlying illness. Once induced, electrolyte disturbances themselves produce symptoms. Sodium depletion (hyponatraemia) may be associated with lowered blood pressure, abdominal pain, weakness.. dizziness, apathy, and, with progression, coma. Potassium depletion (hypokalaemia) may produce lethargy, anorexia, anxiety, depression, muscle weakness, and electrocardiographic ab normalities. Hypocalcaemia may produce depression and muscle cramps; hypercalcaemia may also produce depression and, if severe or prolonged, psychotic or dementia-like symptoms.
The presence of functioning uterine tissue in parts of the body outside the uterus (such as ovaries, umbilicus, laparotomy scars). The ectopic tissue responds to hormonal stimuli with cyclic menstrual bleeding, leading to dysmenorrhea and pelvic pain.
A measure of the expression, by a relative (or fellow workers, neighbours, etc.), of attitudes of emotional involvement with, or of criticism and hostility towards, a patient, in the context of a standardized semi-structured interview (the Camberwell Family Interview).
Lack of expected normal physiological development in a child, including slowed acquisition of developmental milestones and lack of weight gain, often accompanied by lack of growth, physical retardation, and short stature. In the absence of organic causes, failure to thrive may occur as part of .the syndrome of reactive attachment disorder.
Food refusal and extreme faddiness in the presence of an adequate food supply and a reasonably competent care-giver, and the absence of organic disease. There may or may not be associated rumination (repeated regurgitation without nausea or gastrointestinal illness).
Spontaneous recurrence of the visual distortions, physical symptoms, loss of ego boundaries, or intense emotions that occurred when the individual ingested hallucinogens in the past. Flashbacks are episodic, of short duration (seconds to hours), and may duplicate exactly the symptoms of previous hallucinogen episodes. They are sometimes precipitated by fatigue, alcohol intake, or marijuana intoxication. Flashbacks are relatively common and are believed to occur in 25% or more of hallucinogen users.
Fight or flight response, consisting of sympathetic nervous system discharge, mediated by adrenal catecholamine release. Synonyms: flight reflex; sympathetic reaction
A state of dissociative amnesia, plus purposeful travel beyond the usual everyday range. Although there is amnesia for the period of the fugue, the individual’s behaviour during this time may appear completely normal to independent observers.
Frequent, repeated episodes of gambling that dominate the individual’s life to the detriment of social, occupational, material, and family values and commitments. Synonym: compulsive gambling
A conviction of being either male or female, resulting from the combined effects of biological and psychosocial factors.
An inner conviction of one’s femaleness or maleness that is not consonant with the biologically determined sex. Included are transsexualism, dual-role transvestism, and gender identity disorder of childhood. Gender-role disorder is included as an unspecified gender identity disorder.
A response by a bereaved person to the loss, which characteristically proceeds from a phase of shock and bewilderment, via a depressive preoccupation with the deceased, to a gradual period of resolution. Deviations from this sequence are common, and morbid patterns of grieving may constitute a frank depressive illness.
A polypeptide that is secreted by specialized acidophil cells of the anterior pituitary under the control of the hypothalamus. It promotes and regulates somatic and skeletal growth and influences carbohydrate, fat, and protein metabolism. Deficiency of growth hormone results in dwarfism, and excess hormone produces gigantism and acromegaly. Synonyms: human growth hormone; somatotropic hormone; somatotropin
Repeated acts that have no clear rational motivation, cannot be controlled, and generally harm the individual’s interests and those of other people. The individual reports that the behaviour is associated with impulses to action. Included are pathological gambling, pathological fire-setting, pathological stealing, trichotillomania, and other impulse disorders such as intermittent explosive disorder.
A sensory perception, of any modality, occurring in the absence of the appropriate external stimulus. In addition to the sensory modality in which they occur, hallucinations may be subdivided according to their intensity, complexity, clarity of perception, and the subjective degree of their projection into the external environment. Hallucinations may occur in normal individuals in the half-sleeping (hypnagogic) or half-waking (hypnopompic) state. As morbid phenomena they may be symptomatic of cerebral disease, functional psychoses, and the toxic effects of drugs, each with characteristic features.
Describes exaggerated gesture, expression, and speech associated with acting. When applied to personality, the term denotes an aggregation of morbid traits, including theatrical behaviour, a desire to impress, gain sympathy, or be the centre of attention, shallowness of emotion, and intense day dreaming.
Expressions of despair, anger, guilt, withdrawal, and fear, and frequently the development of somatic symptoms that the individual interprets as evidence of a physical decline due to HIV infection or AIDS. Such reactions are particularly frequent immediately after the discovery of seropositivity and in conjunction with changes in the patient’s clinical state.
A state of trance, superficially resembling sleep, induced by suggestion of relaxation and concentrated attention on a single object, in which the individual becomes suggestible and responsive to the hypnotist’s influence and may recall forgotten events and obtain relief from psychological symptoms.
Outlook and attitude of a child or adolescent who is excessively uncertain about personal beliefs and purposes, with consequent impairment of function.
The capacity to resist an impulsive desire or an urge to indulge in self-gratifying behaviour without regard for the consequences.
A severe form of thought and speech disorder in which the prominent features are distortion of grammar, unexplained shifts from topic to topic, and lack of a logical connection between parts of speech.
Unsatisfactory quantity and/or quality of sleep, which persists for a considerable period of time. It includes difficulty .in falling asleep, difficulty in staying asleep, or early final awakening.
An undue state of overreaction involving annoyance, impatience, or anger. It may appear in states of fatigue or chronic pain, or be a clinical feature of temperamental anomalies associated with advancing age, cerebral trauma, epileptic states, and manic-depressive disorders.
A form of Wernicke aphasia (receptive, central, or sensory aphasia) characterized by speech in which syntax seems normal but content is meaningless. Synonym: nonsensical speech
See psychotic disorder, alcohol- or drug-induced.
A form of tabes occurring in children with congenital syphilis or in children who have acquired the disease in infancy or early childhood. The clinical features are those of the adult form of the disease; optic atrophy and mental deterioration are often prominent and the Wasserman reaction may be negative. The untreated course of the disease tends to be one of rapid progression. See also: syphilis, congenital
A form of neurosyphilis occurring in childhood in which the clinical features of general paresis are associated with those of tabes dorsalis. See also: syphilis, congenital; general paresis
A rare syndrome, occurring mostly in young males, characterized by periodic attacks of megaphagia, hypersomnia, and psychological and behavioural disorders. The disorder tends to be self-limiting and may respond to the administration of sympathomimetic amines.
A syndrome of predominant and lasting reduction of memory span, including striking loss of recent memory, disordered time appreciation, and confabulation, occurring in alcohol-dependent individuals as a sequel to an acute alcoholic psychosis (especially delirium tremens) or, more rarely, in the course of the alcohol dependence syndrome. It is usually accompanied by peripheral neuritis and may be associated with Wernicke encephalopathy. First described in 1889 by Korsakov.
A transmissible progressive degenerative disease of the central nervous system, involving primarily the basal ganglia and the cerebellum, and manifest as gross ataxia, athetosis, tremor, dysarthria, and rigidity. Mental changes include emotional lability, psychomotor slowing, and a rapidly progressing dementia. The condition is invariably fatal, death occurring within 6-9 months of onset. The causative agent has been shown by Gajdusek to be an unconventional slow virus with a very long incubation period, closely related to the viral agent suspected in Creutzfeldt-Jakob disease and, possibly, scrapie.
A specific developmental disorder in which the child’s ability to use expressive spoken language is markedly below the appropriate level for its mental age, but language comprehension is within normal limits. There may or may not be abnormalities in articulation. Synonym: developmental dysphasia or aphasia, expressive type
Changes that occur as part of passing from one stage to another in the course of maturation and development, and in particular the behaviour and role-function adaptations that an individual is called upon to make in response to age-related changes over which he or she has little if any control.
Problems in dealing effectively with one’s social, occupational, or interpersonal environment.
A subtype of temporal lobe epilepsy in which pathophysiological changes related to kindling in the mesolimbic system are suspected to lead to the gradual development of personality and behaviour alteration, to severe mood disorders, or to schizophrenia-like psychosis.
A primary malignant lymphoma of the brain to which individuals with HN infection are susceptible. The lesions, more often unifocal than multifocal, involve proliferation of atypical lymphocytes in a perivascular distribution. In some cases, the lymphoma responds to early aggressive radiation therapy.
Any of the games or activities of childhood that depend on the child’s imagination or ability to pretend. The ability to use toys and household objects appropriately is one measure of the child’s comprehension and ability to communicate.
A term originating in the Hippocratic tradition (4th century BC), used until the end of the 19th century to denote generally the depressive syndrome. While Kraepelin and others restricted its use to refer only to depression in the elderly, Freud redefined it as a morbid counterpart of normal mourning. Amidst a general decline in its use, DSM-IIF resurrected the term by giving it yet another meaning in which the distinct quality of depressed mood and the exact opposite of normal mourning are the prominent features. In view of this lack of precision, and the contradictory connotations, the continued use of the term is not recommended.
A range of mental disorders grouped together on the basis of their having in common a demonstrable etiology in cerebral disease, brain injury, or other insult, leading to cerebral dysfunction. The dysfunction may be primary, as in diseases, injuries, and insults that affect the brain directly and selectively, or secondary, as in systemic diseases and disorders that attack the brain only as one of the multiple organs or body systems involved. The term symptomatic mental disorders refers to the latter subgroup.
Recurrent paroxysmal attacks of headache that are variable in intensity, frequency, and duration. The attacks are commonly unilateral and are usually accompanied by anorexia, nausea, and vomiting. In some cases they are preceded by, or associated with, neurological disturbances especially affecting the field of vision. In some cases migraine can present with psychiatric symptoms. The condition is ascribed to vasomotor disturbance of the cerebral circulation.
The apparent existence of two or more distinct or independent personalities within the individual, with only one of them evident at a time.
Psychopathological or neurological manifestations of a diminution or loss of normal function resulting from a lesion in the central nervous system. The concept derives from the dissolution theory of Hughlings Jackson (1835-1911), which postulated a dual effect of cerebral lesions: deficits directly due to the lesion, and positive phenomena arising secondarily as ontogenically lower levels are released from the control of the superior centre. This view has had repercussions in psychiatry, notably in the descriptive psychopathology of schizophrenia. Symptoms usually referred to as negative include poverty of speech, impairment of attention, affective blunting, apathy, and social withdrawal. However, there is no general agreement on the nature and the assessment of the negative symptoms, and little is known about their pathophysiological basis in schizophrenia.
A mental disorder without any demonstrable organic basis, in which the patient may have considerable insight and has unimpaired reality testing, in that he or she usually does not confuse morbid subjective experiences and fantasies with external reality. Behaviour may be greatly affected although usually remaining within socially acceptable limits. Personality is not disorganized. The principal manifestations include excessive anxiety, hysterical symptoms, phobias, obsessive and compulsive symptoms, and depression.
Periodic episodes of repetitive, stereotyped muscle jerks occurring during sleep and followed by partial arousal or awakening. It is usually associated with insomnia and/or daytime sleepiness, and with the restless legs syndrome. The cause is unknown.
Refers to all information-processing and coping skills, such as visual motor coordination and other psychomotor skills, that do not depend primarily on language or verbal responsiveness.
An ill defined concept with several quite different meanings. Those most relevant to health are: habitual; innocuous; optimal or fittest; average or medium; a metrical variate with a particular probability value.
The essential feature is recurrent attacks of severe anxiety (panic), which are not restricted to any particular situation or set of circumstances and are therefore unpredictable. As with other anxiety disorders, the dominant symptoms vary from person to person but may include sudden onset of palpitations, chest pain, choking sensations, dizziness, and feelings of unreality (depersonalization or dereali zation). There is often also a secondary fear of dying, losing control or going mad. Panic disorder must be distinguished from panic attacks occurring as part of established phobic anxiety disorders. Panic attacks may also be secondary to depressive disorders.
Loss of motor power attributable to functional or organic disorder of neuromuscular or neural mechanisms.
A rare chronic psychosis in which logically constructed systematized delusions have developed gradually without concomitant hallucinations or the schizophrenic type of disordered thinking. The delusions are mostly of grandeur (the paranoiac prophet or inventor), persecution, or somatic abnormality.
A neurological disorder, first described by Parkinson (1755-1824), consisting of a degeneration of the basal ganglia, particularly the substantia nigra. The principal clinical features are muscular rigidity, bradykin esia, tremor, and postural deformities. The causes may be idiopathic, infectious, or toxic, or the condition may be part of a wide pathological process affecting the central nervous system, e.g. cerebrovascular disease. Parkinsonian symp toms (parkinsonism) may also be induced by drugs, e.g. neuroleptics, which produce blockade of dopamine receptors in the basal ganglia.
A variety of conditions and behaviour patterns of clinical significance that tend to be persistent and appear to be the expression of the individual’s lifestyle and mode of relating to self and others. Specific personality disorders, mixed personality disorders, and enduring personality change are deeply ingrained and persisting behaviour patterns, manifested as inflexible responses to a broad range of personal and social situations. They represent extreme or significant deviations from the way in which the average individual in a given culture perceives, thinks, feels, and, particularly, relates to others. Included in this group are: habit and impulse disorders, gender identity disorders, sexual preference disorders, sexual development and orientation disorders, elaboration of physical symptoms for psychological reasons, and intentional production or feigning of symptoms.
Weight divided by the second power of height multiplied by 100; an anthropometric index proposed in 1835 and still widely used to quantify the relation between height and weight in the diagnostic assessment of eating disorders.
A term employed to designate a group of psychoses causally related to a preceding external event, e.g. personal loss, bereavement, insult, natural disaster. The psychoses are mostly of brief duration, often but not always remitting with the recession of the provoking factor. Their form and content tend to reflect the nature of the precipitant and to fall into three broad clinical categories: disorders of consciousness (confusional), disorders of affect (depression), and delusional disorders (paranoid). This classification of the reactive psychoses, originally delineated by 1’\’immer in 1916 as psychogenic psychoses, is widely but not universally accepted.
A specific and significant impairment in the development of reading skills that is not solely accounted for by mental age, visual acuity problems, or inadequate schooling. Reading comprehension skill, reading word recognition, oral reading skill, and performance of tasks requiring reading may all be affected. Spelling difficulties are frequently associated with specific reading disorder and often continue into adolescence even after some progress has been made in reading. Specific developmental disorders of reading are commonly preceded by a history of disorders in speech or language development. Associated emotional and/or behavioural disturbances are com mon during the school-age period.
As applied to disability, the combined and coordinated use of medical, social, educational, and vocational measures for training or retraining the individual to the highest possible level of functional ability.
Periods of sleep lasting an average of 5 minutes, which recur in the adult about every 90 minutes and during which rapid eye movements can be recorded by electrooculography. REM (or paradoxical) sleep periods are almost entirely occupied by vivid dreaming, and accompanied by a variety of physiological changes in the pulse rate, respiration, muscle tone, and cerebral blood flow.
Deep, ill-defined paraesthesias of the legs which are experienced principally during prolonged muscular rest, states of drowsiness, and the pre-dormal period. The symptoms are relieved by moving the legs or by walking. The condition may be familial and is often associated with nocturnal myoclonus.
An episodic disorder in which both affective and schizophrenic symptoms are prominent, so that the episode of illness does not justify a diagnosis of either schizophrenia or a depressive or manic episode. Manic, depressive, and mixed types can be distinguished, depending on the preponderant features of the affective ingredient.
A disorder characterized in general by fundamental and characteristic distortions of thinking and perception, and affects that are inappropriate or blunted. Clear consciousness and intellectual capacity are usually maintained, although certain cognitive deficits may evolve in the course of time. The disturbance involves the most basic functions that give the normal person a feeling of individuality, uniqueness, and self-direction. The most intimate thoughts, feelings, and acts are often felt to be known or shared by others, and explanatory delusions may develop, to the effect that natural or supernatural forces are at work to influence the afflicted individual’s thoughts and actions in ways that are often bizarre. Although no strictly pathognomonic symptoms can be identified, the most important psychopathological phenomena include thought echo, thought insertion or withdrawal, thought broadcasting, delusional perception, and delusions of control, influence or passivity, hallucinatory voices commenting on or discussing the patient in the third person, disorders in the train of thought, catatonia, and negative symptoms. The course of schizophrenia can be continuous, or episodic with progressive or stable deficit following the episodes, or consist of one or more episodes with complete remissions.
Any substance that diminishes the activity of an organ or tissue; more specifically, the class of pharmacological substances that moderate excitement and induce a state of calm by their depressing action on the central nervous system. In higher doses they can induce sleep and general anaesthesia.
A wariness of strangers and social apprehension or anxiety when encountering new, strange, or socially threatening situations. Such fears arise during early childhood, but are severe enough to cause problems in social functioning.
A transient disorder that develops in an individual without any other apparent mental disorder in response to exceptional physical and/or mental stress and that usually subsides within hours or days. Individual vulnerability and coping capacity play a role in the occurrence and severity of acute stress reactions. The symptoms show a typically mixed and changing picture and include an initial state of “daze”, with some constriction of the field of consciousness and narrowing of attention, inability to comprehend stimuli, and disorientation. This state may be followed either by further withdrawal from the surrounding situation (to the extent of a dissociative stupor), or by agitation and over-activity (flight reaction or fugue). Autonomic signs of panic anxiety (tachycardia, sweating, flushing) are commonly present. The symptoms usually appear within minutes of the impact of the stressful stimulus or event, and disappear within 2-3 days (often within hours). Partial or complete amnesia for the episode may be present.
A sensation of tightness, pressure, or dull pain that may be generalized or, more typicaliy, have a band-like quality. As a transient disturbance, it is commonly associated with the stresses of everyday life but, when persistent, may be a presenting feature of an anxiety state or a depressive illness.
The experience of one’s own thoughts being repeated or echoed (but not spoken aloud) within one’s head. The interval between the original thought and its echo is usually only a few seconds. The repeated thought, though identical in content, may be felt as slightly altered in quality.
Thyroxine or any of the other active agents secreted by the thyroid gland, including triiodothyronine and thyrocalcitonin. Excessive secretion in hyperthyroidism is characterized by accelerated basal metabolic rate, weakness, weight loss, nervousness, and, particularly in middle-aged or older individuals, cardiac arrhythmia or congestive heart failure.
Decrease in response to a drug dose that occurs with continued use of the drug. In the frequent or heavy drinker, for example, higher doses of alcohol are needed to achieve the effects originally produced by lower doses. Both physiological and psychosocial factors may be involved in the production of tolerance.
A restriction of peripheral vision, with unimpaired central visual acuity, occurring in retinitis pigmentosa and advanced chronic glaucoma. The term is also used as a synonym for tubular vision, a dissociative symptom of hysteria, in which the area of the visual field is the same regardless of the distance of the eye from the focal point.
Any intrinsic force of which the individual is not fully aware that serves to initiate, maintain, or direct behaviour towards a goal. Many systems of psychology assume the presence of an unconscious portion of the mental apparatus containing memories, wishes, impulses, etc. that are not within the immediate field of awareness but that none the less have significant effects on behaviour.
The study of the victims of malteatment, including not only the immediate reaction to the traumatic event but also such issues as how they came to be the objects of attack the kind of physical or psychological assault they were forced to endure, the type of support they might need to return to their usual level of functioning, the long-term consequences of their experience, and the type of restitution or compensation they might merit.
The manipulation of visual data within the central nervous system: an object is perceived and then coded into a form that can be stored and, ultimately, retrieved. Among the elements included in visual processing are discrimination of visual stimuli, visual sequencing, directionality, and visual association.
Inadequate vitamin B12, often a nutritional deficiency secondary to insufficient absorption of the vitamin from the ileum in individuals with long-standing gastrointestinal disease. A frequent result is subacute degeneration of the spinal cord, optic nerves, cerebral white matter, and peripheral nerves. Spinal cord involvement is manifested as combined system disease, characterized by symmetrical progressive paraesthesias of the feet or hands (numbness, tingling, burning, etc.), followed by unsteadiness of gait and finally spasticity, ataxia, and paraplegia. Psychological symptoms include apathy, irritability, suspiciousness, and, with progression, confusion and dementia.
The act of giving utterance, of making sounds or words, used most often to refer to the panicky scream that typically signals the onset of an episode of sleep terror, or to the involuntary repetition of a vowel, word, or phrase that occurs as a characteristic element in some types of focal epilepsy. Vocalization is also used to refer to the sounds made by infants before they acquire regular speech.
Any mental or behavioural disorder due to the use of volatile solvents. When inhaled, volatile solvents (also called inhalants) such as glue, aerosol paints, industrial solvents, lacquer thinners, gasoline, and cleaning fluids produce altered states of consciousness. In addition, some solvents are directly toxic to the liver, kidney, or heart, and some produce peripheral neuropathy or progressive brain degeneration. The user typically soaks a rag with inhalant and places it over the mouth and nose, or puts the inhalant in a paper or plastic bag which is then put over the face (inducing anoxia as well as intoxication). Signs of intoxication include belligerence, assaultiveness, lethargy, psychomotor retardation, euphoria, impaired judgement, dizziness, nystagmus, blurred vision or diplopia, slurred speech, tremors, unsteady gait, hyperreflexia, muscle weakness, stupor, or coma.
An inability to comprehend spoken or written language, and in particular to understand or report spoken language and to name objects or qualities. Reading and writing are secondarily impaired. The lesion, generally vascular, is usually in the association cortex of the first temporal convolution of the dominant hemisphere. In children, this impairment may occur as a specific developmental disorder
An acute, life-threatening, neurological syndrome (described as polioencephalitis haemorrhagica superior in 1881) consisting of confusion, apathy, dullness, a dreamy delirium, palsies of the ocular muscles and of gaze (due to lesions in the nuclei of cranial nerves Ill and VI), nystagmus and · disturbances in equilibrium (due to lesions in the vestibular nuclei), and ataxia (due to lesions in the cerebellar cortex). Its most common cause in industrialized countries is thiamine deficiency associated with alcoholism. If not treated immediately with replacement therapy, the patient is likely to progress into Korsakov psychosis (also known as Wernicke-Korsakov psychosis or syndrome, and as alcohol amnestic disorder}: severe anterograde amnesia, retrograde amnesia, and sometimes confabulation.
A group of symptoms of variable clustering and degree of severity occurring on absolute or relative withdrawal of a substance after persistent use of that substance. The onset and course are time-limited and are related to the type of substance and dose being used immediately before cessation or reduction of use. The withdrawal state may be complicated by convulsions or delirium.
An impaired ability to appreciate spoken language, usually attributable to damage to the cerebral receptive area for hearing in the first temporal gyrus of the dominant hemisphere. In its pure form the condition is rare.
The ready and easy flow of words in speaking. In expressive language disorder, impairment of word fluency and output may be manifested in speech that is halting and hesitant, with a restricted vocabulary and excessive use of generalizations; sentences may be abnormally short or telegrammatic because of omission of conjunctions and prepositions.